Author: Isabelle SutherlandThe impacts of poverty extend beyond having your power turned off and being unable to afford rent. It affects the body internally, particularly in early brain development and cognitive ability. The National Institutes of Health (NIH) has conducted numerous studies examining the development of the cerebral cortex in impoverished children, consistently finding a decrease in volume of gray matter compared to children from more financially secure households. Household eligibility for the federal poverty line is determined by family size and total income. In the United States, the average family typically has two children, with a mean federal poverty threshold of $21,250 per year for this family size (American Council on Aging, 2025). A cross-sectional study with 389 child participants found that those whose household’s income was 1.5 times above the federal poverty line had a 3-4% reduction in gray matter in the frontal cortex (related to higher level cognitive processes), temporal cortex (auditory and emotional processing), and the hippocampus (site of declarative and episodic memory). For children living at the federal poverty line, gray matter reductions were significantly greater, ranging from 8% to 9% (Hair et al., 2015). These results align with a study conducted by the NIH (Tomalski et al., 2013), which used electroencephalogram (EEG) technology to investigate baseline brain activity in the gamma frequency range (linked to higher-order executive functions) of 6- to 9-month-old infants from lower socioeconomic status families. The EEGs recorded lower high-frequency brain activity in the prefrontal cortex, suggesting potential disruptions in cognitive functions related to attention, decision-making, problem-solving, and emotional regulation as the infants mature (Tomalski et al., 2013).
Reduced cortical mass in the brain is an equifinal event that cannot be restricted to socioeconomic status. Restriction of resources extended to the child, such as food resulting in poor nutrition, inadequate housing, and lack of access to healthcare can occur due to many factors and are not exhaustive in contributing to poor brain development. Excessive exposure to loud noises, regular chaos, and conflict among family members can serve as chronic stressors to a child causing the release of the stress hormone cortisol. Elevated levels of this hormone are associated with changes in the volume of the amygdala (a brain region responsible for processing fear and anxiety), as well as atrophy of the hippocampus and dendrites of pyramidal neurons critical to communication between the prefrontal cortex and numerous regions throughout the brain (Liston et al., 2006). Consequently, stress responses that hinder problem-solving and planning could potentially develop heightened reactivity and difficulties with attention and social cognition. Poverty is a multifactorial issue, meaning there is not one solution to resolve it. However, there are actions that can counteract its negative effects. Positive parenting behaviors are attributed to lower cortisol levels in children and higher executive function. Despite the socioeconomic status of a child’s household, they are far more likely to be well-adjusted with a parent that offers warmth, affection, and emotional support. Screening children and their parents for mental health risks, followed with referrals to services is another way to reduce potential stress impact on a child. With the appropriate guidance, improvements in mental health and parenting styles can be achieved (Luby et al., 2018). Several studies have demonstrated that high-quality education can combat poor brain development (Luby et al., 2018) by significantly improving neurocognitive ability, regulation of attention, and the speed at which information is processed (Blair & Raver, 2015). One step in fighting poverty is to help parents build higher levels of human capital in order to increase their federal and state incomes so they can rise above the poverty line (Luby et al., 2018). America’s College Promise Act is a proposed bill that aims to drastically lower the cost of community, technical, and tribal colleges for lower-income adults (Granville, 2023). If passed through legislation, young parents could attend college and strengthen their earning potential to exit poverty and its associated stressors. By helping parents who are struggling financially to rise economically and deliver intentional parenting approaches, impoverished children can have greater opportunities for success, improving their developmental outcomes. References American Council on Aging. (2025). Federal poverty guidelines / levels for 2025 & their relevance to Medicaid eligibility. MedicaidPlanningAssistance.org. https://www.medicaidplanningassistance.org/federal-poverty-guidelines/. Blair, C., & Raver, C. C. (2015). Closing the achievement gap through modification of neurocognitive and neuroendocrine function: Results from a cluster randomized controlled trial of an innovative approach to the education of children in kindergarten. Proceedings of the National Academy of Sciences, 112(43), 13775–13780. https://doi.org/10.1073/pnas.1512276112. Granville, P. (2023, October 17). How America’s College Promise would reshape the free college landscape. The Century Foundation. https://tcf.org/content/report/how-americas-college-promise-would-reshape-the-free-college-landscape/ Hair, N. L., Hanson, J. L., Wolfe, B. L., & Pollak, S. D. (2015). Association of child poverty, brain development, and academic achievement. JAMA Pediatrics, 169(9), 822–829. https://doi.org/10.1001/jamapediatrics.2015.1475. Liston, C., Miller, M. M., Goldwater, D. S., & others. (2006). Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. Journal of Neuroscience, 26(30), 7810–7818. https://doi.org/10.1523/JNEUROSCI.1245-06.2006 Luby, J., Belden, A., Harms, M. P., Tillman, R., & Barch, D. (2018). Poverty, stress, and brain development: New directions for prevention and intervention. JAMA Pediatrics, 172(9), 810–811. https://doi.org/10.1001/jamapediatrics.2018.1326. Tomalski, P., Moore, D. G., Ribeiro, H., & others. (2013). Socioeconomic status and functional brain development—Associations in early infancy. Developmental Science, 16(5), 676–687. https://doi.org/10.1111/desc.12079
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Author: Ashley Lopez-Hernandez Thirteen-year-old AJ Peterman is one of many children benefiting from mobile EEG testing, a groundbreaking approach pioneered by psychologist Caitlin Hudac at the University of South Carolina. As part of her research in the Brain Research Across Development (B-RAD) lab, Dr. Hudac and her team bring their equipment directly into participants’ homes, making it easier for families—especially those in underserved areas—to participate in autism and neurodevelopmental research. According to Erskine (2025) in the article "USC Psychologist Uses Mobile EEG to Break Down Barriers," Hudac and her team share AJ’s experience as a participant in their study. AJ, who is autistic, first joined the research after his mother, Akira Peterman, sought resources for autistic children in their community. Living in Sumter, South Carolina, the Peterman family faces long commutes to access specialized services. To address this challenge, Hudac’s team set up their mobile EEG lab in the Petermans’ home, allowing AJ to comfortably undergo his eighth EEG test while engaging in familiar activities, such as watching videos and interacting with family members. A More Accessible Approach to ResearchThis mobile approach was born out of necessity during the COVID-19 pandemic when travel restrictions disrupted Hudac’s initial research plans. Rather than pause her research, she traveled across the country, testing more than 55 participants with rare genetic conditions such as GRIN2B, SCN2A, and SETBP1 in 90 days. This shift not only made participation easier for families but also improved the testing experience—children felt more at ease in their familiar surroundings, especially those with complex medical symptoms like epilepsy, motor delays, and autism. Now, with funding from the SETBP1 Society, the Orphan Disease Center, and a McCausland Faculty Fellowship, Hudac’steam continues to expand its reach. While studying rare genetic conditions linked to autism, they also rely on neurotypical and autistic participants like AJ to form comparison groups, helping researchers build a more complete picture of autism and neurodevelopmental differences. By comparing EEG measurements across different ages and diagnoses, they aim to understand how rare genetic conditions influence development and their connection to autistic symptoms. Hudac, S. (2025, March 14). "There's a lot of evidence to suggest that all autism is genetic. It's just a matter of have we discovered it or not," Hudac explains. "We currently know about a quarter of autism cases are linked to a known genetic etiology, which is important to emphasize." In Laura Erskine, USC psychologist uses mobile EEG to break down barriers to research. While Hudac’s team has traveled across the U.S. to test children with the SETBP1 gene variant, their long-term goal is to expand internationally to reach more families affected by rare disorders. Expanding and Representation in ScienceDr. Hudac's goal is to make mobile EEG testing accessible not only to participants with rare genetic disorders but also to individuals like AJ’s family in rural communities who face challenges traveling to USC’s lab. By bringing research directly to families, Hudac aims to broaden participation in neuroscience studies and ensure more inclusive representation in autism research. ReferenceErskine, L. (2025, March 14). USC psychologist uses mobile EEG to break down barriers to research. University of South Carolina. https://www.sc.edu/uofsc/posts/2025/03/hudac-mobile-eeg-research.php
Author: Veronica du PlessisOur recent discussion centered around an article titled “Depression Among Older Adults: A 20-Year Update on Five Common Myths and Misconception”. This article revisited a 1997 study that challenged five myths about depression in older adults, highlighting new insights on the subject. The findings of this article hold the potential to positively impact the mental health community as they challenge outdated assumptions that may have led to misdiagnosis, undertreatment, or ineffective interventions for older adults. If depression is better recognized and treated in this population, it could lead to improved quality of life, increased independence, and even longer life expectancy. On a broader scale, changing the conversation about mental health in aging populations can reduce stigma, ensuring that older individuals feel empowered to seek and receive the mental health care they need.
The article listed the first myth that depression is more common in older adults than in younger individuals. Earlier studies suggested that aging led to increased sadness and depressive symptoms. However, more recent research, such as Blazer (2003), has demonstrated that the prevalence of Major Depressive Disorder (MDD) is actually lower in older adults compared to middle-aged individuals. This shift in understanding is partly due to improved diagnostic tools and a better distinction between normal aging and clinical depression (Cole & Dendukuri, 2003). Another evolving perspective involves the causes of depression in older adults. Historically, psychological factors like grief and loneliness were considered the primary triggers. While these factors remain relevant, more recent studies emphasize biological and social determinants, including chronic illness, neurobiological changes, and social isolation, as key contributors (Fiske, Wetherell, & Gatz, 2009). This change in understanding has led to more comprehensive treatment approaches that incorporate medical, psychological, and social factors. Similarly, earlier beliefs suggested that depression manifests differently in older adults, primarily through physical symptoms rather than emotional distress. While some studies, such as Gallo et al. (1994), found a slight increase in bodily symptom complaints among older individuals, more recent research has shown that the overall symptom profile of depression remains consistent across age groups. This understanding has led to improved screening methods that ensure older adults receive appropriate diagnoses rather than attributing their symptoms solely to physical health conditions. The notion that depression in older adults is more chronic and treatment-resistant has also been reevaluated. While it is true that relapse rates are higher due to medical comorbidities and cognitive decline (Mitchell & Subramaniam, 2005), newer findings suggest that psychotherapy, particularly cognitive-behavioral therapy (CBT), is just as effective in older populations as in younger ones (Areán & Cook, 2002). Furthermore, while some earlier research indicated that antidepressant medications might be less effective in older adults, recent studies have focused on optimizing dosages and combining treatments for better outcomes (Nelson et al., 2008). The major findings of the article encompassed that Major Depressive Disorder in older adults is a complex issue influenced by many factors. The treatment, severity, and outcomes of depression depends on more variables such as health conditions than strictly age. The content of the article sparked exciting discussion, in which multiple implications of the article were brought to light. The increased awareness that depression in older adults is often linked to chronic health conditions and social isolation could place additional strain on healthcare systems. If depression is seen as part of a broader network of medical and social issues, treatment must extend beyond prescribing medication and include comprehensive care models- requiring more resources and coordination. Additionally, the research indicating that depression in older adults is more likely to relapse (Mitchell & Subramaniam, 2005) suggests that long-term treatment and follow-up care are crucial, potentially requiring sustained investment in geriatric mental health services. Furthermore, we discussed the social implications of such misconceptions, in particular stigma around mental health in aging. By challenging the myth that depression is a normal part of growing older, older adults may feel more encouraged to seek treatment. As a final note, we analyzed what factors could contribute to the establishment and continuation of misconceptions about mental health in the older age population, such as ageism, previous gaps in research, and the current focus on depression in younger age groups. Haigh, E. A. P., Bogucki, O. E., Sigmon, S. T., & Blazer, D. G. (2018). Depression Among Older Adults: A 20-Year Update on Five Common Myths and Misconceptions. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 26(1), 107–122. https://doi.org/10.1016/j.jagp.2017.06.011 Liv MaceIn our recent discussion in neuroscience, we discussed the social and professional implications of late autism diagnoses. We read a systematic review by Russell et al. (2025), which revealed that the definition of a “late" diagnosis proved remarkably inconsistent across research literature, with studies presenting age ranges from 3 to 18 years. We think this was due to the paper’s consideration for inclusive samples. The average age of diagnosis across all the studies mentioned in the paper was 11.5, which surprised some of us as we had assumed most would have been diagnosed shortly after entering elementary school at the latest. We looked at the significance of diagnostic timing, and we agree that early intervention can optimize brain development and support if sought out early enough by the age of 3.
We also explored the value of late diagnosis by recognizing they offer more than just clinical categorization. While an early diagnosis is preferred, for many individuals a later diagnosis still provides crucial validation, explaining lifelong experiences of differentness. A diagnosis at any stage offers a framework for understanding their own personal experiences. Late diagnoses can also be valuable for individuals to afford healthcare since a diagnosis is necessary for treatment and interventions. Additionally, the emerging trend of self-diagnosis, which we believe has been amplified through social media platforms and an abundance of time available to people during COVID-19, brought a shift in our discussion. We talked about the delicate balance between respecting individual experiences while also maintaining scientific integrity. We do believe that self-identification can provide meaningful personal insights, but it can also present challenges for standardized research methodologies that require precise diagnostic criteria. Lastly, we discussed the outcome of self-diagnoses compared to traditional diagnoses and how this can contribute towards stereotypes. Ultimately, diagnoses need to be based on the DSM5 to uphold scientific integrity. We agree that diagnoses, especially in autism spectrum disorder, is not a simple process of checking diagnostic boxes but an exploration of individual experiences best guided by the help of a licensed professional. The process of diagnosing autism is complex, and our discussion this week aimed to acknowledge this to better understand and communicate with individuals who participate in our studies. Russell, A. S., McFayden, T. C., McAllister, M., Liles, K., Bittner, S., Strang, J. F., & Harrop, C. (2025). Who, when, where, and why: A systematic review of “late Author: Maggie JohnsonBecause it avoids the in-person cues that make social interaction difficult, social media has become a tool for many autistic individuals, offering a space to form relationships in ways that feel more natural and accessible. Unlike in-person interactions, online communication removes challenges like eye contact and physical processing, making it easier to engage. In the article we discussed, (Using social media to be ‘social’: Perceptions of social media benefits and risk by autistic young people, and parents) one adolescent shared, “It helps you build friendships with individuals around the world,” while another noted that it feels “not as personal, more free to speak out.” Many autistic individuals in the study preferred online spaces or video games for socializing opposed to in-person, as they reduce sensory overload and allow for more controlled interactions. With this, we found value in the use of social media for autistic adolescents to be able to strengthen and build social relationships.
Beyond social media, we mentioned some alternative formats to support autistic individuals in developing social skills. We discussed some of the initiatives we have seen, which involved robots that guided interactions and augmented reality that simulating es real conversations. These sought to provide safe, structured environments for communication practice for autistic adolescents. Some of our team questioned whether online interactions should be seen as a complement rather than a supplement for face-to-face engagement. This brought up the idea that we may be able to use this online socialization as a scaffold for more productive in-person opportunities, like playing Roblox with friends in the same physical space instead of playing solely online. We additionally analyzed discussed how online and in-person interactions operate under different social rules. While digital spaces provide vital opportunities for autistic individuals to connect, they don’t always translate seamlessly to real-world relationships. The goal may not be to replace one with the other but to find ways to integrate both, ensuring that autistic individuals have access to meaningful, enjoyable social experiences—online and offline. |
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